A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation

• Những tác giả chính: Peifeng Tang (Tác giả), Jianlin Xu (Tác giả), Christopher L. Oliveira (Tác giả), Zheng Jian Li (Tác giả), Shijie Liu (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

As a key enzyme for glycolysis, lactate dehydrogenase (LDH) remains as a topic of great interest in cancer study. Though a number of kinetic models have been applied to describe the dynamic behavior of LDH, few can reflect its actual mechanism, making it difficult to explain the observed substrate a...