Testing the efficacy of a multi-component DNA-prime/DNA-boost vaccine against Trypanosoma cruzi infection in dogs.

• Main Authors: José E Aparicio-Burgos (Author), Laucel Ochoa-García (Author), José Antonio Zepeda-Escobar (Author), Shivali Gupta (Author), Monisha Dhiman (Author), José Simón Martínez (Author), Roberto Montes de Oca-Jiménez (Author), Margarita Val Arreola (Author), Alberto Barbabosa-Pliego (Author), Juan C Vázquez-Chagoyán (Author), Nisha Jain Garg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging infectious disease in the United States.We tested the efficacy of a multi-component DNA-prime/DNA-boost vaccine (TcVac1) against experimental T. cruzi infection in a cani...