N,N-Dimethyl-D-erythro-Sphingosine Inhibits Store-Operated Ca2+ Entry in U937 Monocytes

• Hlavní autoři: Ji-Yeong Jo (Autor), Hyo-Lim Kim (Autor), Yun-Kyung Lee (Autor), Hideaki Tomura (Autor), Yoe-Sik Bae (Autor), Fumikazu Okajima (Autor), Dong-Soon Im (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2008-01-01T00:00:00Z.
• Témata: article
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Calcium is a ubiquitous second messenger that controls a broad range of cellular functions, and store-operated calcium entry (SOCE) is the primary mechanism of regulated Ca2+ entry in non-excitable immunocytes. In this study, we found that N,N-dimethyl-D-erythro-sphingosine (DMS) inhibited SOCE. In...