Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo.

• Main Authors: Caroline S de Freitas (Author), Luiza M Higa (Author), Carolina Q Sacramento (Author), André C Ferreira (Author), Patrícia A Reis (Author), Rodrigo Delvecchio (Author), Fabio L Monteiro (Author), Giselle Barbosa-Lima (Author), Harrison James Westgarth (Author), Yasmine Rangel Vieira (Author), Mayara Mattos (Author), Natasha Rocha (Author), Lucas Villas Bôas Hoelz (Author), Rennan Papaleo Paes Leme (Author), Mônica M Bastos (Author), Gisele Olinto L Rodrigues (Author), Carla Elizabeth M Lopes (Author), Celso Martins Queiroz-Junior (Author), Cristiano X Lima (Author), Vivian V Costa (Author), Mauro M Teixeira (Author), Fernando A Bozza (Author), Patrícia T Bozza (Author), Nubia Boechat (Author), Amilcar Tanuri (Author), Thiago Moreno L Souza (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Yellow fever virus (YFV) is a member of the Flaviviridae family. In Brazil, yellow fever (YF) cases have increased dramatically in sylvatic areas neighboring urban zones in the last few years. Because of the high lethality rates associated with infection and absence of any antiviral treatments, it i...