The role of s-palmitoylation in neurological diseases: implication for zDHHC family

• Main Authors: Dan Liao (Author), Yutao Huang (Author), Dan Liu (Author), Haofuzi Zhang (Author), Xinyu Shi (Author), Xin Li (Author), Peng Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

S-palmitoylation is a reversible posttranslational modification, and the palmitoylation reaction in human-derived cells is mediated by the zDHHC family, which is composed of S-acyltransferase enzymes that possess the DHHC (Asp-His-His-Cys) structural domain. zDHHC proteins form an autoacylation inte...