In vitro and in situ effects of atorvastatin and ezetimibe on P-glycoprotein expression and function

• Main Authors: Mehran Mesgari Abbasi (Author), Hadi Valizadeh (Author), Hamed Hamishehkar (Author), Maryam Bannazadeh Amirkhiz (Author), Parvin Zakeri-Milani (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P-glycoprotein (P-gp) is a membrane transporter responsible for the active efflux from the cell. Inhibition of the activity may lead to clinically significant drug-drug interactions. This study was performed to investigate the effects of atorvastatin and ezetimibe on the function and expression of P...