In vitro and in situ effects of atorvastatin and ezetimibe on P-glycoprotein expression and function

• Главные авторы: Mehran Mesgari Abbasi (Автор), Hadi Valizadeh (Автор), Hamed Hamishehkar (Автор), Maryam Bannazadeh Amirkhiz (Автор), Parvin Zakeri-Milani (Автор)
• Формат: ‌
• Опубликовано: Bangladesh Pharmacological Society, 2016-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

P-glycoprotein (P-gp) is a membrane transporter responsible for the active efflux from the cell. Inhibition of the activity may lead to clinically significant drug-drug interactions. This study was performed to investigate the effects of atorvastatin and ezetimibe on the function and expression of P...