Paneth-cell-disruption-induced necrotizing enterocolitis in mice requires live bacteria and occurs independently of TLR4 signaling
Necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality in premature infants. Both human surgical specimens and animal models suggest a potential involvement of Paneth cells in NEC pathogenesis. Paneth cells play critical roles in epithelial homeostasis, innate immunity an...
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Main Authors: | Jessica R. White (Author), Huiyu Gong (Author), Brock Pope (Author), Patrick Schlievert (Author), Steven J. McElroy (Author) |
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Format: | Book |
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The Company of Biologists,
2017-06-01T00:00:00Z.
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