Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats
The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions (mr-ASD) by a thin film freezing (TFF) process. Three types of CBZ-mr-ASD with immediate-, delayed-, and controlled-release...
Saved in:
Main Authors: | Houli Li (Author), Meimei Zhang (Author), Lilong Xiong (Author), Weiyi Feng (Author), Robert O. Williams (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-10-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Influence of Carbamazepine Dihydrate on the Preparation of Amorphous Solid Dispersions by Hot Melt Extrusion
by: Xiangyu Ma, et al.
Published: (2020) -
Mechanisms of increased bioavailability through amorphous solid dispersions: a review
by: Andreas Schittny, et al.
Published: (2020) -
Explaining the Release Mechanism of Ritonavir/PVPVA Amorphous Solid Dispersions
by: Adrian Krummnow, et al.
Published: (2022) -
Polymer-Surfactant System Based Amorphous Solid Dispersion: Precipitation Inhibition and Bioavailability Enhancement of Itraconazole
by: Disang Feng, et al.
Published: (2018) -
Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability
by: Jaewook Kwon, et al.
Published: (2019)