Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions

• Main Authors: Hui Zhong (Author), Hidenori Wake (Author), Keyue Liu (Author), Yuan Gao (Author), Kiyoshi Teshigawara (Author), Masakiyo Sakaguchi (Author), Shuji Mori (Author), Masahiro Nishibori (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The apoptotic process of erythrocytes is known as eryptosis, and is characterized by phosphatidylserine (PS) expression on the outer membrane. PS-positive erythrocytes are increased in sepsis, and PS is believed to facilitate coagulation of erythrocytes and activate macrophages. However, the relatio...