Use of a PD-1 checkpoint inhibitor in a patient with ultra-high-risk gestational trophoblastic neoplasia and gastrointestinal metastases

• Glavni autori: Amalia Brawley (Autor), Casey Moffitt (Autor), Shaina Feldman Bruce (Autor), Caitlin Stashwick Farabaugh (Autor), Edward Podczaski (Autor), Joel Sorosky (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2024-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Gestational trophoblastic neoplasia (GTN) are rare diseases that are typically chemo-responsive. While the majority of patients are cured with chemotherapy alone, a small portion of cases are fatal due to chemotherapy resistance. Risk factors for treatment failure are liver and brain metastases, ext...