Potential Therapeutic Targets of Rehmannia Formulations on Diabetic Nephropathy: A Comparative Network Pharmacology Analysis

• Main Authors: Kam Wa Chan (Author), Kam Yan Yu (Author), Wai Han Yiu (Author), Rui Xue (Author), Sarah Wing-yan Lok (Author), Hongyu Li (Author), Yixin Zou (Author), Jinyuan Ma (Author), Kar Neng Lai (Author), Sydney Chi-wai Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Previous retrospective cohorts showed that Rehmannia-6 (R-6, Liu-wei-di-huang-wan) formulations were associated with significant kidney function preservation and mortality reduction among chronic kidney disease patients with diabetes. This study aimed to investigate the potential mechani...