Progressive Sub-MIC Exposure of <i>Klebsiella pneumoniae</i> 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase Genes

• मुख्य लेखकों: Jasmine R. Anderson (लेखक), Nghi B. Lam (लेखक), Jazmyne L. Jackson (लेखक), Sean M. Dorenkott (लेखक), Taylor Ticer (लेखक), Emir Maldosevic (लेखक), Amanda Velez (लेखक), Megan R. Camden (लेखक), Terri N. Ellis (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Bacterial exposure to antibiotic concentrations below the minimum inhibitory concentration (MIC) may result in a selection window allowing for the rapid evolution of resistance. These sub-MIC concentrations are commonly found in soils and water supplies in the greater environment. This study aimed t...