Marked elevation of circulating CD19+CD38hiCD24hi transitional B cells give protection against neonatal sepsis

• Main Authors: Sitao Li (Author), Fei Ma (Author), Hu Hao (Author), Desheng Wang (Author), Yu Gao (Author), Jialiang Zhou (Author), Fei Li (Author), Hung-Chih Lin (Author), Xin Xiao (Author), Qiyi Zeng (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adequate functions of immunoregulation, mediated by regulatory cells such as IL-10 producing CD19+CD38hiCD24hi transitional B cells (Trans), play an important role in control of excessive inflammatory response. Yet, the role of Trans in neonatal sepsis is incompletely understood. We investigated the...