LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation

• Main Authors: Xiaoying Wang (Author), Qian Li (Author), Siyu He (Author), June Bai (Author), Cui Ma (Author), Lixin Zhang (Author), Xiaoyu Guan (Author), Hao Yuan (Author), Yiying Li (Author), Xiangrui Zhu (Author), Jian Mei (Author), Feng Gao (Author), Daling Zhu (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pyroptosis is a form of programmed cell death involved in the pathophysiological progression of hypoxic pulmonary hypertension (HPH). Emerging evidence suggests that N6-methyladenosine (m6A)-modified transcripts of long noncoding RNAs (lncRNAs) are important regulators that parti...