Genome-wide association analysis of anti-TNF-α treatment response in Chinese patients with psoriasis

• Ngā kaituhi matua: Yunqing Ren (Author), Ling Wang (Author), Huatuo Dai (Author), Guiying Qiu (Author), Jipeng Liu (Author), Dianhe Yu (Author), Jianjun Liu (Author), Cheng-Zhi Lyu (Author), Lunfei Liu (Author), Min Zheng (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Background: TNF-α inhibitors are effective biological agents for treating psoriasis, but the treatment responses differ across patients. This study aimed to identify genetic biomarkers of anti-TNF-α response in Chinese psoriasis patients using a genome-wide association approach.Methods: We recruited...