Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials

• Main Authors: Olga Renner (Author), Mascha Mayer (Author), Christian Leischner (Author), Markus Burkard (Author), Alexander Berger (Author), Ulrich M. Lauer (Author), Sascha Venturelli (Author), Stephan C. Bischoff (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The potential of gossypol and of its R-(−)-enantiomer (R-(−)-gossypol acetic acid, AT-101), has been evaluated for treatment of cancer as an independent agent and in combination with standard chemo-radiation-therapies, respectively. This review assesses the evidence for safety and clinical effective...