Mechanisms of oral absorption improvement for insoluble drugs by the combination of phospholipid complex and SNEDDS

• Main Authors: Yingpeng Tong (Author), Qin Zhang (Author), Wen Shi (Author), Jianxin Wang (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

In the present study, a water insoluble drug named silybin was encapsulated into self-nanoemulsifying drug delivery system (SNEDDS) following the preparation of silybin-phospholipid complex (SB-PC), then several methods were carried out to characterize SB-PC-SNEDDS and elucidate its mechanisms to im...