Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking

Inhibition of Ras farnesylation in acute has been found to upregulate the α7 nicotinic acetylcholine receptor (α7nAChR) activity. This study was carried out to investigate the effect of chronic administration for 7 days of farnesyl transferase inhibitor lonafarnib (50 mg/kg, intraperitoneally inject...

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Main Authors: Tingting Chen (Author), Chengyun Cai (Author), Lifeng Wang (Author), Shixin Li (Author), Ling Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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