Quercetin reshapes gut microbiota homeostasis and modulates brain metabolic profile to regulate depression-like behaviors induced by CUMS in rats

• Main Authors: Bozhi Li (Author), Yuqi Yan (Author), Tiange Zhang (Author), Hanfang Xu (Author), Xiaofeng Wu (Author), Gaolei Yao (Author), Xingze Li (Author), Can Yan (Author), Li-Li Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quercetin, an abundant flavonoid compound in plants, is considered a novel antidepressant; however, its mechanisms of action are poorly understood. This study aimed to investigate the therapeutic effects of quercetin on chronic unpredictable mild stress (CUMS)-induced depression-like behaviors in ra...