Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages

• Main Authors: Lin Cao (Author), Erjin Xu (Author), Rendong Zheng (Author), Zhili Zhangchen (Author), Rongling Zhong (Author), Fei Huang (Author), Juan Ye (Author), Hongping Sun (Author), Yaofu Fan (Author), Shaofeng Xie (Author), Yu Chen (Author), Yijiao Xu (Author), Jing Cao (Author), Wen Cao (Author), Chao Liu (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Stimulator of IFN genes (STING) is highly expressed in the livers of non-alcoholic fatty liver disease (NAFLD) patients and high fat diet (HFD) induced NAFLD mice model. The STING signaling-mediated inflammation has been shown to play a critical role in metabolic disorders. Lingg...