Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

• Главные авторы: Schlicker Andreas (Автор), Beran Garry (Автор), Chresta Christine M (Автор), McWalter Gael (Автор), Pritchard Alison (Автор), Weston Susie (Автор), Runswick Sarah (Автор), Davenport Sara (Автор), Heathcote Kerry (Автор), Castro Denis Alferez (Автор), Orphanides George (Автор), French Tim (Автор), Wessels Lodewyk FA (Автор)
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• Опубликовано: BMC, 2012-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Colorectal cancer (CRC) is a heterogeneous and biologically poorly understood disease. To tailor CRC treatment, it is essential to first model this heterogeneity by defining subtypes of patients with homogeneous biological and clinic...