Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

• Main Authors: Schlicker Andreas (Author), Beran Garry (Author), Chresta Christine M (Author), McWalter Gael (Author), Pritchard Alison (Author), Weston Susie (Author), Runswick Sarah (Author), Davenport Sara (Author), Heathcote Kerry (Author), Castro Denis Alferez (Author), Orphanides George (Author), French Tim (Author), Wessels Lodewyk FA (Author)
• Format: Book
• Published: BMC, 2012-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Colorectal cancer (CRC) is a heterogeneous and biologically poorly understood disease. To tailor CRC treatment, it is essential to first model this heterogeneity by defining subtypes of patients with homogeneous biological and clinic...