Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b

• Main Authors: Jin Li (Author), Tingting Yang (Author), Zhao Sha (Author), Haifei Tang (Author), Xuejiao Hua (Author), Lijun Wang (Author), Zitong Wang (Author), Ziyu Gao (Author), Joost P.G. Sluijter (Author), Glenn C. Rowe (Author), Saumya Das (Author), Liming Yang (Author), Junjie Xiao (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The activation of the renin-angiotensin system (RAS) induced by increased angiotensin II (AngII) levels has been implicated in muscle atrophy, which is involved in the pathogenesis of congestive heart failure. Although peroxisome proliferator-activated receptor gamma (PPARγ) activation can suppress...