4',6-Dihydroxy-4-methoxyisoaurone inhibits TNF-α-induced NF-κB activation and expressions of NF-κB-regulated target gene products

• Main Authors: Juan Ma (Author), Chunliu Mi (Author), Ke Si Wang (Author), Jung Joon Lee (Author), Xuejun Jin (Author)
• Formato: Libro
• Publicado: Elsevier, 2016-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The nuclear factor-κB (NF-κB) transcription factors control many physiological processes including inflammation, apoptosis, and angiogenesis. In our search for NF-κB inhibitors from natural resources, we identified 4',6-dihydroxy-4-methoxyisoaurone (ISOA) as an inhibitor of NF-κB activation fro...