Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study

• Main Authors: Yingpeng Huang (Author), Jiali Zhang (Author), Renjie Dong (Author), Xiawei Ji (Author), Yusha Jiang (Author), Jianke Cen (Author), Zhihuai Bai (Author), Kairui Hong (Author), Huihui Li (Author), Jiajing Chen (Author), Jinhui Zhou (Author), Fanyu Qian (Author), Fangyan Wang (Author), Yue Qu (Author), Yan Zhou (Author)
• Format: Book
• Published: BMC, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pre-administration of probiotic Lactobacilli attenuates ethanol-induced gastric mucosal injury (GMI). The underpinning mechanisms remain to be elucidated. We speculated that lactate, the main metabolite of Lactobacillus that can be safely used as a common food additive, mediated...