Molecular genetic investigation of hereditary breast and ovarian cancer patients in the Southern Transdanubian region: widening the mutation spectrum and searching for new pathogenic variants using next-generation methods

• Main Authors: László Baráti (Author), Anita Maász (Author), Alexandra Mikó (Author), Éva Bércesi (Author), Sultan Al Kalbani (Author), Judit Bene (Author), Sebestyén Kovács (Author), László Mangel (Author), Kinga Hadzsiev (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hereditary breast and ovarian cancer is a well-known genetic condition, inherited mainly in an autosomal dominant way, which elevates the risk of developing malignancies at a young age in heterozygous carriers. Advances in new generation sequencing have enabled medical professionals to determine whe...