Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA-IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trialResearch in context

• Main Authors: Dong-Hua Luo (Author), Xiao-Yun Li (Author), Shan-Shan Guo (Author), Wan-Ping Guo (Author), Li-Ting Liu (Author), Hao-Yuan Mo (Author), Ling Guo (Author), Xiao-Fei Lv (Author), Li-Zhi Liu (Author), Ji-Bin Li (Author), Qing Liu (Author), Pan Wang (Author), Xue-Song Sun (Author), Sai-Lan Liu (Author), Qiu-Yan Chen (Author), Lin-Quan Tang (Author), Hai-Qiang Mai (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Previous studies demonstrated that induction chemotherapy (IC) followed by de-escalated chemoradiotherapy adapted to tumor response was effective in treating childhood nasopharyngeal carcinoma (NPC), but the toxicity profile of this treatment strategy, and whether childhood pati...