Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes

• Main Authors: Amy Kenyon (Author), Daria Gavriouchkina (Author), Jernej Zorman (Author), Vanessa Chong-Morrison (Author), Giorgio Napolitani (Author), Vincenzo Cerundolo (Author), Tatjana Sauka-Spengler (Author)
• Format: Book
• Published: The Company of Biologists, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A complex network of inflammatory genes is closely linked to somatic cell transformation and malignant disease. Immune cells and their associated molecules are responsible for detecting and eliminating cancer cells as they establish themselves as the precursors of a tumour. By the time a patient has...