Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitriles as Tubulin Polymerization Inhibitors: Part 2

• मुख्य लेखकों: Anja Beč (लेखक), Lucija Hok (लेखक), Leentje Persoons (लेखक), Els Vanstreels (लेखक), Dirk Daelemans (लेखक), Robert Vianello (लेखक), Marijana Hranjec (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We used classical linear and microwave-assisted synthesis methods to prepare novel <i>N</i>-substituted, benzimidazole-derived acrylonitriles with antiproliferative activity against several cancer cells in vitro. The most potent systems showed pronounced activity against all tested hemat...