Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine.

• Main Authors: Maria Agallou (Author), Maritsa Margaroni (Author), Evita Athanasiou (Author), Dimitra K Toubanaki (Author), Katerina Kontonikola (Author), Konstantina Karidi (Author), Olga Kammona (Author), Costas Kiparissides (Author), Evdokia Karagouni (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Through their increased potential to be engaged and processed by dendritic cells (DCs), nanovaccines consisting of Poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with both antigenic moieties and adjuvants are attractive candidates for triggering specific defense mecha...