RAD51 as a biomarker for homologous recombination deficiency in high‐grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test

• Main Authors: Claire JH Kramer (Author), Alba Llop‐Guevara (Author), Elisa Yaniz‐Galende (Author), Benedetta Pellegrino (Author), Natalja T terHaar (Author), Andrea Herencia‐Ropero (Author), Nicoletta Campanini (Author), Antonino Musolino (Author), Tjalling Bosse (Author), Alexandra Leary (Author), Violeta Serra (Author), Maaike PG Vreeswijk (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The RAD51 test is emerging as a promising biomarker for the assessment of functional homologous recombination deficiency (HRD). Yet, the robustness and reproducibility of the immunofluorescence‐based RAD51 test, in different academic laboratories, have not been systematically investigated....