Design and Synthesis of New Non-Steroidal Anti-inflammatory Agents with Expected Selectivity toward Cyclooxygenase-2 Inhibition

• Autori principali: Nadeem A. Abdul Razzak (Autore), Samera F.Hussan (Autore), Ahlam J. Qaseer (Autore)
• Natura: Libro
• Pubblicazione: College of Pharmacy University of Baghdad, 2017-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with expected cyclooxygenase-2 (COX-2) selective inhibition to achieve better activity and low gastric side effects. Two series of compounds have been designed and synthesized as potential NSAIDs,these  a...