Evidence-based Management of Major Bleeding in Patients Receiving Direct Oral Anticoagulants: An Updated Narrative Review on the Role of Specific Reversal Agents

• Main Authors: Zohair Al Aseri FRCPC EM, CCM (Author), Farjah H. AlGahtani MD, MPH (Author), Majid F. Bakheet MD (Author), Ahmed H. Al-Jedai PharmD (Author), Sarah Almubrik MD (Author)
• Format: Book
• Published: SAGE Publishing, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The indications of direct oral anticoagulants (DOACs) have expanded over the past 15 years. DOACs are effective and safe oral anticoagulants associated with lower bleeding risks and mortality than vitamin K antagonists. However, DOAC users are prone to a considerable bleeding risk, which can occur a...