Predicting the serum digoxin concentrations of infants in the neonatal intensive care unit through an artificial neural network

• Autori principali: Shu-Hui Yao (Autore), Hsiang-Te Tsai (Autore), Wen-Lin Lin (Autore), Yu-Chieh Chen (Autore), Chiahung Chou (Autore), Hsiang-Wen Lin (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2019-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Given its narrow therapeutic range, digoxin's pharmacokinetic parameters in infants are difficult to predict due to variation in birth weight and gestational age, especially for critically ill newborns. There is limited evidence to support the safety and dosage requirements...