Glucose inhibits glucagon secretion by decreasing [Ca2+]c and by reducing the efficacy of Ca2+ on exocytosis via somatostatin-dependent and independent mechanisms
Objective: The mechanisms by which glucose stimulates insulin secretion from β-cells are well established and involve inhibition of ATP-sensitive K+ (KATP) channels, followed by a rise in [Ca2+]c that triggers exocytosis. However, the mechanisms by which glucose controls glucagon release from α-cell...
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| Main Authors: | , , |
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Elsevier,
2022-07-01T00:00:00Z.
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| Klassifikationsnummer: |
A1234.567 |
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| Kopi 1 | Tilgængelig |