Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B₁-Induced Oxidative Damage

• Main Authors: Jinfu Zhang (Author), Siyi Hu (Author), Changzhi Zhao (Author), Yuan Zhou (Author), Lu Zhang (Author), Hailong Liu (Author), Peng Zhou (Author), Sheng Li (Author), Liangliang Fu (Author), Zhuqing Zheng (Author), Yue Xiang (Author), Xuewen Xu (Author), Jinxue Ruan (Author), Xinyun Li (Author), Lvhui Sun (Author), Gang Cao (Author), Shuhong Zhao (Author), Xu Wang (Author), Shengsong Xie (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aflatoxin B₁ (AFB₁) is amongst the mycotoxins commonly affecting human and animal health, raising global food safety and control concerns. The mechanisms underlying AFB₁ toxicity are poorly understood. Moreover, antidotes against A...