Aerobic exercise suppresses CCN2 secretion from senescent muscle stem cells and boosts muscle regeneration in aged mice

• Main Authors: Fan Li (Author), Fulong Zhang (Author), Haiwang Shi (Author), Honglin Xia (Author), Xiaobei Wei (Author), Siqi Liu (Author), Tao Wu (Author), Yuecheng Li (Author), Feng Shu (Author), Mengjie Chen (Author), Jie Li (Author), Rui Duan (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aging negatively impacts tissue repair, particularly in skeletal muscle, where the regenerative capacity of muscle stem cells (MuSCs) diminishes with age. Although aerobic exercise is known to attenuate skeletal muscle atrophy, its specific impact on the regenerative and repair c...