Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro

• Main Authors: Ge Gao (Author), Lingyun Fu (Author), Yini Xu (Author), Ling Tao (Author), Ting Guo (Author), Guanqin Fang (Author), Guangqiong Zhang (Author), Shengquan Wang (Author), Ti Qin (Author), Peng Luo (Author), Xiangchun Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic cardiomyopathy (DCM) is one of the common complications of diabetic patients, which can induce myocardial hypertrophy, cardiac fibrosis, and heart failure. Growing evidence has shown that the occurrence and development of DCM are accompanied by pyroptosis which is an NLRP3-mediated intense...