Degradation behavior of theophylline/chitosan/?-cyclodextrin microspheres for pulmonary drug delivery

• Main Authors: Li Wang (Author), Tingting Yang (Author), Weiping Ju (Author), Ming Ren (Author), Zhanqin Feng (Author), Zengjuan Zheng (Author), Zhenbo Hu (Author), Yuqing Liu (Author), Weifen Zhang (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To evaluate the degradation behavior of theophylline/chitosan/?-cyclo-dextrin microspheres, we performed both in vitro study by putting the microspheres in phosphate buffered saline or in phosphate buffer saline with enzyme and in vivo study by implanting the microspheres into the back of male Sprag...