Role of Tacrolimus C/D Ratio in the First Year After Pediatric Liver Transplantation

• Main Authors: Benas Prusinskas (Author), Sinja Ohlsson (Author), Simone Kathemann (Author), Denisa Pilic (Author), Kristina Kampmann (Author), Rainer Büscher (Author), Andreas Paul (Author), Lars Pape (Author), Peter F. Hoyer (Author), Elke Lainka (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The calcineurin inhibitor (CNI) tacrolimus (TAC) is a cornerstone agent in immunosuppressive therapy in pediatric liver transplantation (LTX). Adverse effects limit the use of CNI. In adults, calculating the individual TAC metabolism rate allows to estimate the transplant recipient'...