Pharmacokinetic study of Strongylocentrotus nudus egg polysaccharide in rats and beagles using a 3H-labeling method

• Main Authors: Han Xing (Author), Xiaojie Zhu (Author), Jianmin Liao (Author), Ying Kong (Author), Yayuan Lu (Author), Di Zhao (Author), Ning Li (Author), Xijing Chen (Author), Zhiying Qin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Strongylocentrotus nudus egg polysaccharide (SEP) extracted from sea urchins has potential anticancer activity. However, little is known about its pharmacokinetic properties. To investigate the pharmacokinetics of SEP, it was radiolabeled with tritium. Furthermore, a sensitive, selective, and rapid...