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Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation

ABSTRACTObjective To investigate the effects of glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide on endothelial dysfunction in LDL receptor-deficient (LDLR-KO) mice and ox-LDL-challenged human umbilical vein endothelial cells (HUVECs) and its possible mechanism.Methods LDLR-KO mice were...

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Bibliographic Details
Main Authors:	Wu Ying (Author), Song Meiyan (Author), Chen Wen (Author), Xu Kaizu (Author), Wu Meifang (Author), Lin Liming (Author)
Format:	Book
Published:	Taylor & Francis Group, 2023-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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