Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis.

• Main Authors: Raymond L Houghton (Author), Dana E Reed (Author), Mark A Hubbard (Author), Michael J Dillon (Author), Hongjing Chen (Author), Bart J Currie (Author), Mark Mayo (Author), Derek S Sarovich (Author), Vanessa Theobald (Author), Direk Limmathurotsakul (Author), Gumphol Wongsuvan (Author), Narisara Chantratita (Author), Sharon J Peacock (Author), Alex R Hoffmaster (Author), Brea Duval (Author), Paul J Brett (Author), Mary N Burtnick (Author), David P Aucoin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the "gold standard" for the diagnosis of melioidosis; results can take 3-7 days to produce. Alternatively, antibody-based tests have low spec...