Early Diagnosis of Wolfram Syndrome by Ophthalmologic Screening in a Patient with Type 1B Diabetes Mellitus: A Case Report

• Main Authors: Takahide Kokumai (Author), Shigeru Suzuki (Author), Noriko Nishikawa (Author), Hinako Yamamura (Author), Tokuo Mukai (Author), Yusuke Tanahashi (Author), Satoru Takahashi (Author)
• Formato: Libro
• Publicado: Galenos Yayincilik, 2024-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Wolfram syndrome (WS) is a monogenic diabetes caused by variants of the WFS1 gene. It is characterized by diabetes mellitus (DM) and optic atrophy. Individuals with WS initially present with autoantibody-negative type 1 DM (type 1B DM; T1BDM). The diagnosis is often delayed or misdiagnosed, even aft...