Antibodies Enhance the Suppressive Activity of Extracellular Vesicles in Mouse Delayed-Type Hypersensitivity

• Main Authors: Katarzyna Nazimek (Author), Eugenio Bustos-Morán (Author), Noelia Blas-Rus (Author), Bernadeta Nowak (Author), Justyna Totoń-Żurańska (Author), Michał T. Seweryn (Author), Paweł Wołkow (Author), Olga Woźnicka (Author), Rafał Szatanek (Author), Maciej Siedlar (Author), Philip W. Askenase (Author), Francisco Sánchez-Madrid (Author), Krzysztof Bryniarski (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we showed that mouse delayed-type hypersensitivity (DTH) can be antigen-specifically downregulated by suppressor T cell-derived miRNA-150 carried by extracellular vesicles (EVs) that target antigen-presenting macrophages. However, the exact mechanism of the suppressive action of miRNA-15...