Telmisartan versus metformin in downregulating myostatin gene expression and enhancing insulin sensitivity in the skeletal muscles of type 2 diabetic rat model

• Main Authors: Ahmed Abd-Eltawab Tammam (Author), Waleed Y. Rizg (Author), Amy Fakhry Boushra (Author), Maha Alhelf (Author), Mohammed Alissa (Author), Ghada F. Soliman (Author), Ghada Nady Ouais (Author), Khaled M. Hosny (Author), Hala M. Alkhalidi (Author), Ahmed Magdy Elebiary (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Telmisartan is an angiotensin receptor blocker (ARB) that specifically blocks angiotensin II type-1 receptors (AT1R). Telmisartan has been proven to have antidiabetic effects via a variety of mechanisms, and it can be utilized in some diabetic patients due to its dual benefit for hyperten...