A Recombinant Positive Control for Serology Diagnostic Tests Supporting Elimination of Onchocerca volvulus.

• Main Authors: Allison Golden (Author), Eric J Stevens (Author), Lindsay Yokobe (Author), Dunia Faulx (Author), Michael Kalnoky (Author), Roger Peck (Author), Melissa Valdez (Author), Cathy Steel (Author), Potochoziou Karabou (Author), Méba Banla (Author), Peter T Soboslay (Author), Kangi Adade (Author), Afework H Tekle (Author), Vitaliano A Cama (Author), Peter U Fischer (Author), Thomas B Nutman (Author), Thomas R Unnasch (Author), Tala de los Santos (Author), Gonzalo J Domingo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Serological assays for human IgG4 to the Onchocerca volvulus antigen Ov16 have been used to confirm elimination of onchocerciasis in much of the Americas and parts of Africa. A standardized source of positive control antibody (human anti-Ov16 IgG4) will ensure the quality of surveillance data using...