Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis.

• Главные авторы: Nittaya Khakhum (Автор), Preeti Bharaj (Автор), Julia N Myers (Автор), Daniel Tapia (Автор), David H Walker (Автор), Janice J Endsley (Автор), Alfredo G Torres (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Предметы: article
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<h4>Background</h4>Glanders caused by Burkholderia mallei is a re-emerging zoonotic disease affecting solipeds and humans. Furthermore, B. mallei is genetically related to B. pseudomallei, which is the causative agent of melioidosis. Both facultative intracellular bacteria are classified...