A cross-reactive monoclonal antibody to nematode haemoglobin enhances protective immune responses to Nippostrongylus brasiliensis.

A cross-reactive monoclonal antibody to nematode haemoglobin enhances protective immune responses to Nippostrongylus brasiliensis.

BACKGROUND: Nematode secreted haemoglobins have unusually high affinity for oxygen and possess nitric oxide deoxygenase, and catalase activity thought to be important in protection against host immune responses to infection. In this study, we generated a monoclonal antibody (48Eg) against haemoglobi...

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Main Authors: Natalie E Nieuwenhuizen (Author), Jeanne M Meter (Author), William G Horsnell (Author), J Claire Hoving (Author), Lizette Fick (Author), Michael F Sharp (Author), Matthew G Darby (Author), Suraj P Parihar (Author), Frank Brombacher (Author), Andreas L Lopata (Author)
Format: Book
Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
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