Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum.

• Main Authors: Rahel Wampfler (Author), Natalie E Hofmann (Author), Stephan Karl (Author), Inoni Betuela (Author), Benson Kinboro (Author), Lina Lorry (Author), Mariabeth Silkey (Author), Leanne J Robinson (Author), Ivo Mueller (Author), Ingrid Felger (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean children per...