Glycerol not lactate is the major net carbon source for gluconeogenesis in mice during both short and prolonged fasting

• Hauptverfasser: Yujue Wang (Verfasst von), Hyokjoon Kwon (Verfasst von), Xiaoyang Su (Verfasst von), Fredric E. Wondisford (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2020-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Objective: Fasting results in major metabolic changes including a switch from glycogenolysis to gluconeogenesis to maintain glucose homeostasis. However, the relationship between the length of fasting and the relative contribution of gluconeogenic substrates remains unclear. We investigated the rela...